Salaries › Physician Assistant › South Carolina
Physician Assistant Salary in South Carolina (2026)
$58.89 per hour · take-home ≈ $88,796/year ($7,400/month) for a single filer
South Carolina ranks 45th of 51 states for Physician Assistant pay, with a median about 13% below the national average. Of the 2,250 Physician Assistant jobs BLS counts in South Carolina, the typical worker earns $122,490 a year — though pay ranges from $77,620 for newcomers to $158,860 at the top.
Physician Assistant pay range in South Carolina
| Percentile | Annual wage | Meaning |
| 10th percentile (entry) | $77,620 | Lowest-paid 10% earn less than this |
| 25th percentile | $105,560 | A quarter earn less |
| Median (50th) | $122,490 | Half earn more, half earn less |
| 75th percentile | $134,100 | Top quarter starts here |
| 90th percentile (top) | $158,860 | Highest-paid 10% earn more than this |
BLS reports 2,250 Physician Assistant jobs in South Carolina (occupation code 29-1071, “Physician Assistants”).
Gross vs. take-home in South Carolina
A median Physician Assistant salary of $122,490 doesn’t all reach your bank account. After federal income tax, Social Security, and Medicare, plus South Carolina state income tax, a single filer keeps about $88,796 — an effective tax rate of 27.5%.
| Gross (median) | $122,490 |
| Federal income tax | −$18,132 |
| Social Security + Medicare | −$9,370 |
| South Carolina state income tax | −$6,192 |
| Take-home (annual) | $88,796 |
| Take-home (monthly) | $7,400 |
Want your exact numbers — married, 401(k), different salary? Use the free South Carolina paycheck calculator on PaycheckTally.
Frequently asked questions
- How much does a Physician Assistant make in South Carolina?
- The median Physician Assistant salary in South Carolina is $122,490 per year ($58.89 per hour) according to the latest BLS data. The middle 50% earn between $105,560 and $134,100.
- What is the take-home pay for a Physician Assistant in South Carolina?
- On the median salary of $122,490, a single filer in South Carolina takes home about $88,796 per year ($7,400 per month) after federal tax, FICA, and state income tax — an effective tax rate of 27.5%.
- How many Physician Assistant jobs are there in South Carolina?
- BLS counts 2,250 Physician Assistant jobs in South Carolina in the latest survey (May 2025).
Top-paying states for Physician Assistants
Other salaries in South Carolina
Sources and methodology
Wage and employment figures: BLS OEWS May 2025 (state file, released April 2026) — the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics survey, the most authoritative public salary dataset. Take-home estimate: 2026 federal brackets, FICA, and verified South Carolina state tax rules (single filer, standard deduction, no credits or local taxes). Estimates only — not financial advice.
- BLS OEWS — official occupational wage data.
- PaycheckTally — interactive 2026 take-home calculator for South Carolina.