Salaries › Registered Nurse › South Carolina
Registered Nurse Salary in South Carolina (2026)
$39.60 per hour · take-home ≈ $62,986/year ($5,249/month) for a single filer
Registered Nurse pay range in South Carolina
| Percentile | Annual wage | Meaning |
| 10th percentile (entry) | $66,860 | Lowest-paid 10% earn less than this |
| 25th percentile | $77,320 | A quarter earn less |
| Median (50th) | $82,360 | Half earn more, half earn less |
| 75th percentile | $97,230 | Top quarter starts here |
| 90th percentile (top) | $106,520 | Highest-paid 10% earn more than this |
BLS reports 49,750 Registered Nurse jobs in South Carolina (occupation code 29-1141, “Registered Nurses”).
Gross vs. take-home in South Carolina
A median Registered Nurse salary of $82,360 doesn’t all reach your bank account. After federal income tax, Social Security, and Medicare, plus South Carolina state income tax, a single filer keeps about $62,986 — an effective tax rate of 23.5%.
| Gross (median) | $82,360 |
| Federal income tax | −$9,289 |
| Social Security + Medicare | −$6,301 |
| South Carolina state income tax | −$3,784 |
| Take-home (annual) | $62,986 |
| Take-home (monthly) | $5,249 |
Want your exact numbers — married, 401(k), different salary? Use the free South Carolina paycheck calculator on PaycheckTally.
Frequently asked questions
- How much does a Registered Nurse make in South Carolina?
- The median Registered Nurse salary in South Carolina is $82,360 per year ($39.60 per hour) according to the latest BLS data. The middle 50% earn between $77,320 and $97,230.
- What is the take-home pay for a Registered Nurse in South Carolina?
- On the median salary of $82,360, a single filer in South Carolina takes home about $62,986 per year ($5,249 per month) after federal tax, FICA, and state income tax — an effective tax rate of 23.5%.
- How many Registered Nurse jobs are there in South Carolina?
- BLS counts 49,750 Registered Nurse jobs in South Carolina in the latest survey (May 2025).
Top-paying states for Registered Nurses
Other salaries in South Carolina
Sources and methodology
Wage and employment figures: BLS OEWS May 2025 (state file, released April 2026) — the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics survey, the most authoritative public salary dataset. Take-home estimate: 2026 federal brackets, FICA, and verified South Carolina state tax rules (single filer, standard deduction, no credits or local taxes). Estimates only — not financial advice.
- BLS OEWS — official occupational wage data.
- PaycheckTally — interactive 2026 take-home calculator for South Carolina.