Salaries › Nurse Practitioner › South Carolina
Nurse Practitioner Salary in South Carolina (2026)
$59.28 per hour · take-home ≈ $89,294/year ($7,441/month) for a single filer
Nurse Practitioner pay range in South Carolina
| Percentile | Annual wage | Meaning |
| 10th percentile (entry) | $97,080 | Lowest-paid 10% earn less than this |
| 25th percentile | $107,930 | A quarter earn less |
| Median (50th) | $123,290 | Half earn more, half earn less |
| 75th percentile | $132,220 | Top quarter starts here |
| 90th percentile (top) | $160,170 | Highest-paid 10% earn more than this |
BLS reports 5,670 Nurse Practitioner jobs in South Carolina (occupation code 29-1171, “Nurse Practitioners”).
Gross vs. take-home in South Carolina
A median Nurse Practitioner salary of $123,290 doesn’t all reach your bank account. After federal income tax, Social Security, and Medicare, plus South Carolina state income tax, a single filer keeps about $89,294 — an effective tax rate of 27.6%.
| Gross (median) | $123,290 |
| Federal income tax | −$18,324 |
| Social Security + Medicare | −$9,432 |
| South Carolina state income tax | −$6,240 |
| Take-home (annual) | $89,294 |
| Take-home (monthly) | $7,441 |
Want your exact numbers — married, 401(k), different salary? Use the free South Carolina paycheck calculator on PaycheckTally.
Frequently asked questions
- How much does a Nurse Practitioner make in South Carolina?
- The median Nurse Practitioner salary in South Carolina is $123,290 per year ($59.28 per hour) according to the latest BLS data. The middle 50% earn between $107,930 and $132,220.
- What is the take-home pay for a Nurse Practitioner in South Carolina?
- On the median salary of $123,290, a single filer in South Carolina takes home about $89,294 per year ($7,441 per month) after federal tax, FICA, and state income tax — an effective tax rate of 27.6%.
- How many Nurse Practitioner jobs are there in South Carolina?
- BLS counts 5,670 Nurse Practitioner jobs in South Carolina in the latest survey (May 2025).
Top-paying states for Nurse Practitioners
Other salaries in South Carolina
Sources and methodology
Wage and employment figures: BLS OEWS May 2025 (state file, released April 2026) — the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics survey, the most authoritative public salary dataset. Take-home estimate: 2026 federal brackets, FICA, and verified South Carolina state tax rules (single filer, standard deduction, no credits or local taxes). Estimates only — not financial advice.
- BLS OEWS — official occupational wage data.
- PaycheckTally — interactive 2026 take-home calculator for South Carolina.