Salaries › Medical Assistant › South Carolina
Medical Assistant Salary in South Carolina (2026)
$19.79 per hour · take-home ≈ $33,940/year ($2,828/month) for a single filer
Medical Assistant pay range in South Carolina
| Percentile | Annual wage | Meaning |
| 10th percentile (entry) | $34,730 | Lowest-paid 10% earn less than this |
| 25th percentile | $37,290 | A quarter earn less |
| Median (50th) | $41,160 | Half earn more, half earn less |
| 75th percentile | $46,950 | Top quarter starts here |
| 90th percentile (top) | $49,110 | Highest-paid 10% earn more than this |
BLS reports 12,110 Medical Assistant jobs in South Carolina (occupation code 31-9092, “Medical Assistants”).
Gross vs. take-home in South Carolina
A median Medical Assistant salary of $41,160 doesn’t all reach your bank account. After federal income tax, Social Security, and Medicare, plus South Carolina state income tax, a single filer keeps about $33,940 — an effective tax rate of 17.5%.
| Gross (median) | $41,160 |
| Federal income tax | −$2,759 |
| Social Security + Medicare | −$3,149 |
| South Carolina state income tax | −$1,313 |
| Take-home (annual) | $33,940 |
| Take-home (monthly) | $2,828 |
Want your exact numbers — married, 401(k), different salary? Use the free South Carolina paycheck calculator on PaycheckTally.
Frequently asked questions
- How much does a Medical Assistant make in South Carolina?
- The median Medical Assistant salary in South Carolina is $41,160 per year ($19.79 per hour) according to the latest BLS data. The middle 50% earn between $37,290 and $46,950.
- What is the take-home pay for a Medical Assistant in South Carolina?
- On the median salary of $41,160, a single filer in South Carolina takes home about $33,940 per year ($2,828 per month) after federal tax, FICA, and state income tax — an effective tax rate of 17.5%.
- How many Medical Assistant jobs are there in South Carolina?
- BLS counts 12,110 Medical Assistant jobs in South Carolina in the latest survey (May 2025).
Top-paying states for Medical Assistants
Other salaries in South Carolina
Sources and methodology
Wage and employment figures: BLS OEWS May 2025 (state file, released April 2026) — the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics survey, the most authoritative public salary dataset. Take-home estimate: 2026 federal brackets, FICA, and verified South Carolina state tax rules (single filer, standard deduction, no credits or local taxes). Estimates only — not financial advice.
- BLS OEWS — official occupational wage data.
- PaycheckTally — interactive 2026 take-home calculator for South Carolina.