Salaries › Nurse Practitioner › Missouri
Nurse Practitioner Salary in Missouri (2026)
$62.47 per hour · take-home ≈ $94,904/year ($7,909/month) for a single filer
Nurse Practitioner pay range in Missouri
| Percentile | Annual wage | Meaning |
| 10th percentile (entry) | $100,650 | Lowest-paid 10% earn less than this |
| 25th percentile | $119,910 | A quarter earn less |
| Median (50th) | $129,930 | Half earn more, half earn less |
| 75th percentile | $144,640 | Top quarter starts here |
| 90th percentile (top) | $162,060 | Highest-paid 10% earn more than this |
BLS reports 7,710 Nurse Practitioner jobs in Missouri (occupation code 29-1171, “Nurse Practitioners”).
Gross vs. take-home in Missouri
A median Nurse Practitioner salary of $129,930 doesn’t all reach your bank account. After federal income tax, Social Security, and Medicare, plus Missouri state income tax, a single filer keeps about $94,904 — an effective tax rate of 27.0%.
| Gross (median) | $129,930 |
| Federal income tax | −$19,917 |
| Social Security + Medicare | −$9,940 |
| Missouri state income tax | −$5,169 |
| Take-home (annual) | $94,904 |
| Take-home (monthly) | $7,909 |
Want your exact numbers — married, 401(k), different salary? Use the free Missouri paycheck calculator on PaycheckTally.
Frequently asked questions
- How much does a Nurse Practitioner make in Missouri?
- The median Nurse Practitioner salary in Missouri is $129,930 per year ($62.47 per hour) according to the latest BLS data. The middle 50% earn between $119,910 and $144,640.
- What is the take-home pay for a Nurse Practitioner in Missouri?
- On the median salary of $129,930, a single filer in Missouri takes home about $94,904 per year ($7,909 per month) after federal tax, FICA, and state income tax — an effective tax rate of 27.0%.
- How many Nurse Practitioner jobs are there in Missouri?
- BLS counts 7,710 Nurse Practitioner jobs in Missouri in the latest survey (May 2025).
Top-paying states for Nurse Practitioners
Other salaries in Missouri
Sources and methodology
Wage and employment figures: BLS OEWS May 2025 (state file, released April 2026) — the U.S. Bureau of Labor Statistics Occupational Employment and Wage Statistics survey, the most authoritative public salary dataset. Take-home estimate: 2026 federal brackets, FICA, and verified Missouri state tax rules (single filer, standard deduction, no credits or local taxes). Estimates only — not financial advice.
- BLS OEWS — official occupational wage data.
- PaycheckTally — interactive 2026 take-home calculator for Missouri.